Mrinmayee Takle, MD, is a pediatric neurologist at Pediatric Specialists of Virginia (PSV) who cares for children with a range of neurologic conditions, with particular interests in headache and global health. She is board certified in Neurology with Special Qualification in Child Neurology and sees patients in Fairfax.
Dr. Takle earned her undergraduate degree from Virginia Commonwealth University and her medical degree from the University of Virginia School of Medicine, before completing her residency and fellowship at Children’s National Hospital.
Raised in Northern Virginia, Dr. Takle was drawn to medicine by her interest in science, problem solving, and building long-term relationships with patients and families. She chose pediatric neurology because of the complexity of neurologic disorders and the importance of early intervention in the developing brain. Dr. Takle is particularly interested in headache care, and develops individualized, multimodal treatment plans that help children return to their daily activities and improve their quality of life.
Publications:
Takle M, Conaway M, Burnsed J. Electroencephalogram Background Predicts Time to Full Oral Feedings in Hypoxic-Ischemic Encephalopathy. Am J Perinatol. 2022;39(15):1678-1681. doi:10.1055/s-0041-1725161
https://pubmed.ncbi.nlm.nih.gov/33657637/
Ramwell C, Liomba AM, Takle M, et al. Loss to Hospital Follow-Up in Pediatric Cerebral Malaria Survivors: A Case-Control Study. Am J Trop Med Hyg. 2023;109(5):1077-1080. Published 2023 Sep 25. doi:10.4269/ajtmh.23-0403
https://pubmed.ncbi.nlm.nih.gov/37748770/
Nwanze, C., Muller, D., Suleman, P., Takle, M., Barber, J. R., Wilson, K. J., Beare, N. A. V., Seydel, K. B., & Postels, D. G. (2024). Severity of Vessel Color Changes and Macular and Peripheral Whitening in Malarial Retinopathy Are Associated with Higher Total Body and Sequestered Parasite Burdens. Tropical medicine and infectious disease, 9(11), 279. https://doi.org/10.3390/tropicalmed9110279
https://pubmed.ncbi.nlm.nih.gov/39591285/
Takle, M., Sahjwani, D., Bharucha-Goebel, D., Rapp, T., Bouska, C., Kornbluh, A. and Sen, K. (2025), Pyridoxal phosphate binding protein (PLPBP) deficiency mimicking opsoclonus-myoclonus-ataxia syndrome. Ann Child Neurol Soc, 3: 52-56. https://doi.org/10.1002/cns3.20098
https://onlinelibrary.wiley.com/doi/10.1002/cns3.20098?utm_medium=article&utm_source=researchgate.net
Takle M, Andrews A, Riggle BA, Zelleke T, Harrar D, Zhang J, Zhang B, Wilson KJ, Beare NAV, Taylor TE, Seydel KB, Ray S, Postels DG. Using Electroencephalography to Assess Coma Etiology in Children with Retinopathy-Negative Cerebral Malaria. Am J Trop Med Hyg. 2025 Jul 22;113(4):809-816. doi: 10.4269/ajtmh.25-0377. PMID: 40695269; PMCID: PMC12493243.
https://pubmed.ncbi.nlm.nih.gov/40695269/
Takle M, Strelzik J, Langdon R, Turner A, McClintock W, Barber J, Dejoie A, McCracken E, Goucher O, DiSabella M. Coenzyme Q10 Supplementation May Be Correlated With Resolution of New Daily Persistent Headache. J Child Neurol. 2025 Sep 1:8830738251366866. doi: 10.1177/08830738251366866. Epub ahead of print. PMID: 40888530.
https://pubmed.ncbi.nlm.nih.gov/40888530/
Board Certifications:
- Neurology with Special Qualification in Child Neurology
Education:
Fellowship: Children’s National Hospital
Residency: Children’s National Hospital
Medical School: University of Virginia School of Medicine
Undergraduate: Virginia Commonwealth University
